Sleep
Restless nights deserve a thoughtful plan. Doxylamine and trazodone affect sleepiness, while melatonin helps regulate sleep timing. A clinician reviews your goals, the formula and individual suitability.
From $140.36 /mo equivalent
$421.08 prepaid for 3 months
Medication, shipping, clinician review and ongoing support included.
Renews automatically. Cancel anytime in the portal or email hello@consideritrx.com.
Continue to the secure intake form. An independent clinician reviews your history before any prescribing decision.
Your program, considered
Knockout combines doxylamine, trazodone and melatonin in a dissolving tablet. The ingredients affect sleepiness or sleep timing through different pathways.
Trazodone use for sleep is off-label; the ingredients’ sedating effects can add up and carry into the next day. This compounded combination is not FDA-approved.
See the research & risksClear pricing
Review the medication and strength choices. Your clinician confirms whether treatment fits before any prescription.
Medication, shipping, clinician review and ongoing support included. Longer plans are prepaid at the total shown. Treatment and final terms are confirmed before checkout.
Medication, one shipment for the plan, clinician review and ongoing care-team support are included in eligible priced plans. Your plan includes one synchronous clinical visit per plan month. No separate shipping or clinician-review fee is added.
Longer plans are prepaid at the full total shown; monthly amounts are equivalents. Separately ordered lab testing or optional services require a separate confirmed quote. Review your exact medicine, strength, pharmacy, total and terms before checkout. A prescription is never guaranteed.
Care that considers you
Share your health history, medicines and goals in the secure intake form.
A licensed clinician reviews the evidence, risks and alternatives with you.
If prescribed, confirm the exact formula, directions, full cost and follow-up.
The details that matter
Know the evidence.
Make an informed decision.
The ingredients affect different sleep and brain signals. Their sleepy effects can add up, including the next morning.
Small studies of trazodone suggest some sleep benefits, with possible next-day effects. Those findings do not establish the benefit or safety of the three-ingredient Knockout blend.
Small human trial · 2011
A short trazodone study found improvements in some sleep measures. It also found small problems with memory, balance, and other next-day tasks. The trial did not test Knockout.
Study results are not a promise of personal results. Research on one formula or route does not establish the same results for another.
Knockout is not FDA-approved. Trazodone use for sleep is off-label, and this combined orally disintegrating tablet needs its own review.
Drowsiness, dizziness, and dry mouth can occur. Do not mix with alcohol or add sleep aids on your own. Avoid driving when impaired. Fainting, severe confusion with fever, or a painful erection that will not go away needs urgent care. Get immediate help for suicidal thoughts.
Compounded means a pharmacy makes a custom formula; compounded medicines are not FDA-approved. Off-label means a medicine is used in a way its FDA approval does not cover. Your clinician explains the exact product, risks and alternatives before treatment.
Doxylamine succinate; Trazodone; Melatonin. Your dispensing pharmacy confirms the final prescription label and any inactive ingredients.
Not always. A good plan should improve rest and daytime function. Feeling groggy the next day is a reason to review it.
That depends on the cause of the sleep problem. Sleep-focused therapy, called CBT-I, and changes to habits may help. Your care team should set a follow-up plan.
This program uses odt. Other formulations have their own program pages.
Follow the directions provided with your prescription. Your clinician and dispensing pharmacy confirm the dose, preparation, storage and follow-up. The product image is not a dosing guide.
You can start secure intake now. A licensed clinician reviews your health history, medicines and goals, then confirms whether treatment is appropriate.
This browsing page does not collect medical information. Share health details only in the secure care portal.
Your next chapter
Start with your goals. A licensed clinician helps you understand what fits.
Looking for a clearer approach to falling asleep? Ramelteon targets sleep-timing signals; SleepE combines it with magnesium L-threonate in a chewable tablet. A clinician reviews your goals, the formula and individual suitability.
Medication, shipping, clinician review and ongoing support included.
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